Thursday, July 14, 2005

We just listened to a lecture on Bioinformatics by a leader in the field, Professor Pevzner. It was incredibly interesting... discussion of "genetic faults" in evolution. The lecture asked whether certain genomes are more likely to break than others, somewhat like earthquake faults. Just like California's more likely to have an earthquake than say, Illinois, are certain genomes more likely to have lasting mutations (for the species as a whole) than others? He talked about a concept called breakpoints, which is basically what it sounds like. Points where the DNA strand breaks and rearranges itself (he discussed inversion mainly). Anyway, each rearrangement should create 2 breakpoints at most (you know... left and right...), which should be normal if evolution is random (something like... the Ohno 1973 Random SOMETHING Hypothesis). Of course, you can get one new breakpoint if one breakpoint has already been used- i.e. it's already been broken once. So if everything's random, that should be extremely unlikely. You have about 3 billion genes... what are the odds that the same places will get broken repeatedly? However, there were 260 breakpoints found using some kind of human-mouse similarities graphing superposition and computer analysis (GRIMM maybe?), implying 130 breakpoints, assuming the random hypothesis is correct. However... some scientists managed to predict that in the 80's and confirm in the 90's that there are 245 rearrangments or something... not quite sure on the details. So 245 is significantly greater than 130... it means that each breakpoint was used about 2 times (closer to 1.9). If you think about it... that is extremely unlikely using the random hypothesis. There are 3 billion genes, so chance shouldn't play a big factor in it (I mean, maybe it's just coincidence if there were about 10 genes). So that suggests that certain areas are much more likely to mutate (with a lasting effect). It's supposed to be in the July 2005 issue of Science and written by Murphy et al, and to appear on July 22? I'm not quite sure on the details of that either... It was incredibly interesting, everybody seemed to love it. That is a major contrast from this morning's Discovery Series Lecture (this one was arranged by our professors for our cluster, Discovery is arranged by COSMOS for all clusters). I thought the topic was actually pretty interesting. Building the Brain: From Simplicity to Complexity. The first 3/5 was actually pretty interesting. 2 sections on the basics of the brain, then the 5 steps in the development of the human embryo (which are Tissue Specification, Proliferation, Migration, Differentiation, and Formation of Connections/Synapses), then... I'm not quite sure, I couldn't stay awake. I believe something about Dynamic Development and the role of Electricity in the development of neurons. I wanted to listen, but for some reason I just couldn't keep my eyelids open. Even if they were... the material seemed to be in way too much depth. I was nodding off into sleep all the time... I could stay awake for literally 5-10 seconds before nodding off again. But I managed to figure out that they recorded Calcium spikes (which would indicate neuron firings) and looked at the effects those had on young neurons. I managed to catch that axons would turn... The speaker was a very knowlegable guy, very enthusiastic, good speaker, interesting materials on the screen, good use of videos/iimages but I couldn't stay awake for the last half. I guess overall the course will be interesting. The first 2.5 days weren't exactly great, but I suppose that's just some introductory stuff that we have to cover. The cluster still isn't well-organized, being the first year this has been run at COSMOS, but it should be some interesting material. I've always thought of Computer Science as programming and stuff... Mr. Hochhaus said that it was using computers to solve problems, but everyone, including himself, basically assumed that was using programming to solve programming-esque problems. Well, we've been dumped into a lot of new fields, much of it in way too much depth and which requires a background in the field to get some understanding of it. I mean... learning javascript? Requires com sci background, learning computing power in relationship to computer hardware requires hardware background, bioinfo requires bio background... But it should be quite interesting. We're doing a lot of AI/computer perception stuff, should be fun. Gotta go now...

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4:09 AM  
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4:28 AM  
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4:28 AM  
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4:28 AM  
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4:28 AM  
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4:56 AM  
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4:56 AM  
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4:56 AM  
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4:56 AM  
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4:56 AM  
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4:56 AM  
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5:25 AM  
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6:04 AM  
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6:05 AM  
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6:05 AM  
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6:05 AM  
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6:05 AM  
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10:30 AM  
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Soak up a lot more and eradicate excess excess fat - Do not skip your meal. It is possible to eat three moments daily and nonetheless lose excessive excess fat. In the event you encounter hungry involving your meals you are able to take in fruit juices just because they are really nutritious, simple around the belly and might replenish you quickly. However, you should stay clear of colas and gentle-drinks.Exercising routinely - You should exercise to observe by you lose weight fast. Cardiovascular vascular routines such as running, brisk strolling, swimming and biking are adequate to burn off calories on the daily foundation. If you can command to do human human body developing exercise routine, you may be capable to melt away up fats and even more speedily price.
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These sorts of clubs are available in most cities and cities and so there'll be a slimming club near you. Frequently the conferences last about an hour and they require remaining weighed (obviously) and sharing tons of guidelines and concepts to aid retain you within the suitable monitor. Also deemed an awesome destination to satisfy folks and make like minded associates which will assist you although you might be in your excess weight reduction trip.
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Physical exercise is an additional way which you can go about acquiring quickly excess fat loss. The detail about using physical exercise to attain rapid excess weight reduction is always that it's a minimal bit difficult. With exercise, you could possibly not observe a major body weight reduction right away. For instance, it commonly normally takes most people no less than weekly or two to notice a noticable difference of their look using the use of workout. With that in mind, the greater obese you happen to be, the earlier you could see a lessen in your bodyweight, generally quickly.
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Most of the people believe that if they simply prevent consuming, they are going to lose weight. What usually takes place is the fact that your body goes into starvation mode and starts storing meals which include weight. Moreover, starvation can not realistically be sustained within the long haul so that you can lose weight fast.What also occurs when this foodstuff is being saved to be the body goes into hunger mode, is fat burning capacity is slowed down so as to enable more excess fat for being saved. Starving by yourself or consuming reduced calorie products and solutions won't work within the long run to help you to realize and keep rapid weight loss. Consuming recurrent meals instead of skipping breakfast specifically, will keep your metabolic rate functioning to enable you to lose weight fast.
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